The group raised £253,000 for Cure Leukaemia which helps cancer patients access new treatments.
The challenge will see the 54-year-old West Horsley resident cycle 1,175km (730 miles).
The event celebrates the launch of the new feature film, Ghosts: The Possession of Button House.
West Horsley Place, which is Button House in Ghosts, is being digitally recreated by engineers.
Baschea Walsh says she feels "absolutely sick" to leave the cottage on the estate where the hit sitcom was filmed.
West Horsley Place appears as Button House in the BBC sitcom Ghosts.
Fans are being encouraged to dress as characters from the series for West Horsley Place's open day.
West Horsley Place asked blind and partially-sighted people to help design the community space.
The ride is a fundraiser for a horse riding charity for people with disabilities.
