Susie Fowler-Watt will anchor BBC Look East for the last time in December.
Susie Fowler-Watt says it has been a "privilege" to have "grown up" alongside audiences.
Trump is suing the BBC over an episode of Panorama that edited together two different sections of a speech he gave in 2021.
The station, which started in February 2019, will move to BBC iPlayer in spring next year.
The BBC announced it will close its BBC Three, BBC Scotland and Radio 4 Extra broadcast channels.
The closures are announced as the corporation continues to try to save £500m over two years.
The cast have described plans to leave Birmingham as similar "to Corrie leaving the north-west."
The BBC said all journalism and editorial decisions are made by BBC journalists and editors.
The long-running programme will be replaced by a "more cost-effective" spin-off show revisiting past projects.
