People with ME say new government funding for research into the illness is "a drop in the ocean".
Caroline Murphy is to undertake a 22-mile course after spending years of her life indoors due to illness.
Tomos is one of thousands with ME in Wales, with services described as “a desert” for those most affected.
Gabby Rudge-Cox, 42, says long Covid has "robbed her of a future".
Patients and scientists appeal for government help in moving research forward.
NHS Highland plans to provide the help as part of its long Covid support service.
The £1.1m Rosetta Stone study hopes to make a breakthrough by comparing both conditions.
After an ME diagnosis last year, Harry Boulton, 17, is using the power of music to raise awareness.