The Earl de Grey originally built in 1831, will be used by the charity HEY Smile Foundation.
The plans sees four brownfield sites near the Wolverhampton Science Park being redeveloped.
At the halfway stage most of the projects in England are delayed and only three have been completed.
The owners of a 17th Century hotel in Great Yarmouth that needs urgent work cannot be traced.
The plans include redevelopment to provide housing for 1,800 people in the city centre by 2030.
The former Sainsbury's site at St George's could be transformed into new homes and green spaces.
It is hoped the first homes could be finished in three years, say developers.
People worry the access point from a busy roundabout could add to traffic issues.
People are moving into 61 flats for social rent in a new development in Oxford's Blackbird Leys.