The largest tremor was felt more than 12 miles away from the epicentre in the village of Silverdale.
Tsunami warnings are issued for neighbouring countries as videos of destruction circulate online.
One Silverdale resident said she thought her "ironing board had fallen over in the airing cupboard".
Hundreds have died and thousands are missing after Wednesday's flooding and landslides on the border of Nepal and Tibet.
A 2.2 magnitude earthquake was recorded in Grimsby, experts from the British Geological Survey say.
A magnitude 6.7 earthquake struck the Ayacucho region on Thursday, the US Geological Survey says.
A number of buildings and cars are damaged in the historic city, and the world famous Alhambra palace has temporarily closed.
Some 53 people were killed and thousands displaced by the earthquake, which struck early on Saturday.
Hundreds of homes and public buildings have been severely damaged with at least 53 people killed.
