Private healthcare company Cigna has put 129 jobs at risk in Greenock, adding to hundreds of job losses in the area.
Whitbread says it will also remodel its 197 hotel restaurants as part of a five-year savings plan.
Other tech giants Alphabet, Microsoft and Amazon also reported quarterly earnings on Wednesday.
The cuts, which employees had been expecting for weeks, will be Meta's largest layoff since 2023.
The Snapchat owner is laying off around 16% of staff and withdrawn hundreds of open job roles.
MP Linsey Farnsworth has told the BBC she understood 80 redundancies had been made at the firm.
It is thought that thousands of people may have lost their jobs at Oracle, one of the world's largest tech companies.
More tech leaders are pointing to job cuts caused by AI tools - and a need for more investment cash.
Staff at the island's only end-of-life care provider have been offered voluntary redundancy amid financial concerns.