BBC Science Editor Rebecca Morelle reflects on how it felt to watch history being made.
The boots worn by astronauts on the Artemis missions will need to protect them from difficult terrain and extreme temperatures, but what about the prints they leave behind?
As the astronauts pass behind the Moon they will experience a moment of silence and solitude as communication with the Earth is blocked.
Resident are urged to join a cosmic quest for micrometeorites from space landing in their gutters.
There was giddy euphoria at the Kennedy Space Center after the launch, writes the BBC's Pallab Ghosh.
Science editor Rebecca Morelle watched from just three miles away as the most powerful rocket ever built blasted off from Florida.
After delays and technical issues, the first crewed Moon mission in 50 years finally took off from Florida and is now in Earth's orbit.
From spacesuit fitting to final communications checks in the rocket, the crew prepared for liftoff to begin their 10-day mission.
Artemis II will take a team of four astronauts further from Earth than any other human has in history when it orbits around the far side of the Moon.