The Ellangowan Hotel in Creetown became the Green Man pub for the 1970s cult horror movie.
A restricted zone for Dumfries and Galloway and parts of Ayrshire will be put in place on Thursday.
A control zone covering most of Dumfries and Galloway and parts of Ayrshire has been put in place.
The news came after restrictions were introduced on the movement of animals in Dumfries and Galloway.
Six cases, including in Lockerbie, have been recorded in Scotland so far after a poorly lamb in Creetown caught the virus earlier this month.
Fiona says she is worried about bluetongue in her stock and for other farmers' livestock.
Fiona Johnson moved her family to Creetown earlier this year, hoping to start afresh with animals bought from the local area - but "bad luck" intervened.
Scotland's first ever case of the virus was detected in a lamb in Dumfries and Galloway on Saturday.
It comes after Scotland's first ever case was confirmed in Dumfries and Galloway earlier this week.
